🦴与FOP相关的ALK2 R206H突变赋予BMP I型受体的构成活性,并使间充质细胞对BMP诱导的成骨细胞分化和骨形成敏感ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP‐induced osteoblast differentiation and bone formation