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📇 文献索引
THE MEDICAL MANAGEMENT OF FIBRODYSPLASIA OSSIFICANS PROGRESSIVA: CURRENT TREATMENT CONSIDERATIONS
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ICC
Published
icc-fop-guidance
Dec 17, 2023
大会讨论热点之一是今年最新发现的控制靶点MMP-9，MMP-9的发现标志着FOP以及其他疾病导致的异位骨化，又新增了一个控制靶点，实验室数据说明此靶点对于控制异位骨化极其有效。
Post
Published
2024-FOP-Summit
Oct 16, 2024
卡普兰教授提到了这位同时带有 FOP 经典点位 R206 突变及 MMP-9 相关基因点突变的患者。 笔者在大会现场见到该病人，目测该病人全身主要关节活动正常，仅仅在颈背部略有一些僵 硬感，其它活动与常人无明显异常。
Post
Published
2024-FOP-XiaowenPapa-noted
Oct 16, 2024
International physician survey on management of FOP: a modified Delphi study
4359840
Post
研究
推荐
热门文章
ICC
Published
modified_Delphi_study
Dec 24, 2023
Special considerations for clinical trials in fibrodysplasia ossificans progressiva (FOP)
52916494
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研究
推荐
必看精选
ICC
Published
Special-considerations-for-clinical-trials
Dec 24, 2023
Fibrodysplasia ossificans progressiva: diagnosis, management, and therapeutic horizons.
3995352
Post
研究
ICC
Published
fop-diagnosis-management-therapeutic-horizons
Oct 6, 2024
Fibrodysplasia ossificans progressiva: Clinical course, genetic mutations and genotype-phenotype correlations.
13118947
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研究
ICC
Invisible
Clinical_course_genetic_mutations_genotype_phenotype_correlations
Oct 5, 2024
Deterioration of pulmonary function: An early complication in Fibrodysplasia Ossificans Progressiva.
232293598
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研究
ICC
Invisible
deterioration-of-pulmonary-function
Oct 6, 2024
Inherited human disease of heterotopic bone formation.
25205044
Post
研究
ICC
Invisible
human-disease-of-heterotopic-bone-formation
Oct 6, 2024
The phenotype of fibrodysplasia ossificans progressiva.
71339634
Post
研究
ICC
Invisible
the-phenotype-of-fop
Oct 6, 2024
A cumulative analogue joint involvement scale (CAJIS) for fibrodysplasia ossificans progressiva (FOP).
4053040
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研究
ICC
Invisible
CAJIS-for-fop
Oct 6, 2024
Early mortality and cardiorespiratory failure in patients with fibrodysplasia ossificans progressiva.
45511250
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研究
ICC
Invisible
early-mortality-and-cardiorespiratory-failure
Oct 6, 2024
Mast cell involvement in fibrodysplasia ossificans progressiva (FOP).
22897027
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研究
ICC
Invisible
Mast-cell-involvement
Oct 7, 2024
Modeling the ACVR1 R206H mutation in human skeletal muscle stem cells.
243940371
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研究
ICC
Invisible
Modeling-the-ACVR1-R206H
Oct 7, 2024
An Acvr1 Knock-in mouse has fibrodysplasia ossificans progressiva.
34484544
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研究
ICC
Invisible
An-Acvr1-Knock-in-mouse
Oct 7, 2024
The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization
14118736
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研究
ICC
Invisible
BMP-independent-chondrogenesis
Oct 7, 2024
ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP‐induced osteoblast differentiation and bone formation
207269687
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研究
ICC
Published
ALK2-R206H-mutation-linked
Oct 7, 2024
Acute lymphocytic infiltration in an extremely early lesion of fibrodysplasia ossificans progressiva.
39487901
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研究
ICC
Invisible
Acute-lymphocytic-infiltration
Oct 7, 2024
A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva
41579747
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研究
ICC
Invisible
A-recurrent-mutation-in-the-BMP
Oct 7, 2024
Dynamics of skeletal muscle-resident stem cells during myogenesis in fibrodysplasia ossificans progressiva
245936653
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研究
ICC
Invisible
Dynamics-of-skeletal muscle-resident
Oct 7, 2024
Fibrodysplasia ossificans progressiva mutant ACVR1 signals by multiple modalities in the developing zebrafish.
221540720
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研究
ICC
Invisible
ACVR1-signals-by-multiple-modalities
Oct 7, 2024
Elevated BMP and Mechanical Signaling Through YAP1/RhoA Poises FOP Mesenchymal Progenitors for Osteogenesis
159039771
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研究
ICC
Invisible
Elevated-BMP-and-Mechanical-Signaling
Oct 7, 2024
Dysregulated BMP signaling and enhanced osteogenic differentiation of connective tissue progenitor cells from patients with fibrodysplasia ossificans progressiva (FOP).
24767611
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研究
ICC
Invisible
Dysregulated-BMP-signaling
Oct 7, 2024
Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressiva.
25407404
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研究
ICC
Invisible
Structure-of-the-bone-morphogenetic
Oct 7, 2024
Cartilage-derived retinoic acid-sensitive protein (CD-RAP): A stage-specific biomarker of heterotopic endochondral bone ossification (HEO) in fibrodysplasia ossification progressiva (FOP).
4147494
Post
研究
ICC
Invisible
Cartilage-derived-retinoic
Oct 7, 2024
ACVR1(R206H) receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A.
34831835
Post
研究
ICC
Invisible
imparting-responsiveness-to-activin-A
Oct 7, 2024
Variable signaling activity by FOP ACVR1 mutations.
4348282
Post
研究
ICC
Invisible
Variable-signaling-activity
Oct 7, 2024
Neofunction of ACVR1 in fibrodysplasia ossificans progressiva.
12329263
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研究
ICC
Invisible
Neofunction-of-ACVR1
Oct 7, 2024
The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling.
12436217
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研究
ICC
Invisible
The-FOP-metamorphogene-encodes
Oct 7, 2024
Pathogenic ACVR1 R206H activation by Activin A-induced receptor clustering and autophosphorylation.
234769488
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研究
ICC
Invisible
Pathogenic-ACVR1-R206H
Oct 7, 2024
Fibrodysplasia ossificans progressiva: A clue from the fly?
26642757
Post
研究
ICC
Invisible
A-clue-from-the-fly
Oct 7, 2024
ACVR1 R206H FOP mutation alters mechanosensing and tissue stiffness during heterotopic ossification.
53198741
Post
研究
ICC
Invisible
ACVR1-R206H-FOP-mutation-alters
Oct 7, 2024
In vitro analysis of dysregulated R206H ALK2 kinase-FKBP12 interaction associated with heterotopic ossification in FOP.
32990783
Post
研究
ICC
Invisible
In-vitro-analysis-of-dysregulated
Oct 7, 2024
Alk2 regulates early chondrogenic fate in fibrodysplasia ossificans progressiva heterotopic endochondral ossification.
21519639
Post
研究
ICC
Invisible
Alk2-regulates-early-chondrogenic
Oct 7, 2024
Reduced GS Domain Serine/Threonine Requirements of Fibrodysplasia Ossificans Progressiva Mutant Type I BMP Receptor ACVR1 in the Zebrafish.
Post
研究
ICC
Invisible
Reduced-GS-Domain-Serine
Oct 7, 2024
Functional modeling of the ACVR1 (R206H) mutation in FOP.
11493870
Post
研究
ICC
Invisible
Functional-modeling-of-the-ACVR1
Oct 7, 2024
Plasma‐Soluble Biomarkers for Fibrodysplasia Ossificans Progressiva (FOP) Reflect Acute and Chronic Inflammatory States
245504485
Post
研究
ICC
Invisible
Plasma‐Soluble-Biomarkers
Oct 7, 2024
Urinary basic fibroblast growth factor: a biochemical marker for preosseous fibroproliferative lesions in patients with FOP.
35739793
Post
研究
ICC
Invisible
Urinary-basic-fibroblast
Oct 7, 2024
Hematopoietic stem cell contribution to ectopic skeletogenesis.
33411836
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研究
ICC
Invisible
Hematopoietic-stem-cell-contribution
Oct 7, 2024
The histopathology of fibrodysplasia ossificans progressiva: an endochondral process.
28979008
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研究
ICC
Invisible
an-endochondral-process.
Oct 7, 2024
Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva.
45414950
Post
研究
ICC
Invisible
Activin-dependent-signaling-in-fibro
Oct 7, 2024
Fibrodysplasia ossificans progressiva: a current review of imaging findings.
24391905
Post
研究
ICC
Invisible
fop-a-current-review-of-imaging-findings
Oct 6, 2024
Proximal tibial osteochondromas in patients with fibrodysplasia ossificans progressiva.
34996704
Post
研究
ICC
Invisible
Proximal-tibial-osteochondromas
Oct 6, 2024
Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification.
25252314
Post
研究
ICC
Invisible
Multipotent-progenitors-resident
Oct 7, 2024
Depletion of Mast cells and macrophages impairs heterotopic ossification in an ACVR1 (R206H) mouse model of fibrodysplasia ossificans progressiva.
206009783
Post
研究
ICC
Invisible
Depletion-of-Mast-cells-and-macrophages
Oct 7, 2024
The face signature of fibrodysplasia ossificans progressiva.
34532055
Post
研究
ICC
Invisible
The-face-signature
Oct 6, 2024
The natural history of fibrodysplasia ossificans progressiva: A prospective, global 36-month study.
252497288
Post
研究
ICC
Invisible
a-prospective-global-36-month-study
Oct 6, 2024
Cellular hypoxia promotes heterotopic ossification by amplifying BMP signaling.
33020658
Post
研究
ICC
Invisible
Cellular-hypoxia-promotes
Oct 7, 2024
Identification of progenitor cells that contribute to heterotopic skeletogenesis.
36703177
Post
研究
ICC
Invisible
Identification-of-progenitor-cells
Oct 7, 2024
The natural history of flare-ups in fibrodysplasia ossificans progressiva: a comprehensive global assessment.
45246651
Post
研究
ICC
Invisible
fop-natural-history-of-flare-ups
Oct 6, 2024
[18F]NaF PET/CT scan as an early marker of heterotopic ossification in fibrodysplasia ossificans progressiva.
4275682
Post
研究
ICC
Invisible
petct-scan-as-an-early-marker
Oct 6, 2024
Radiographic and scintigraphic features of modeling and remodeling in the heterotopic skeleton of patients who have fibrodysplasia ossificans progressiva.
36163228
Post
研究
ICC
Invisible
Radiographic-and-scintigraphic-features
Oct 6, 2024
Fibrodysplasia ossificans progressiva（Mahboubi-2001）
Post
研究
ICC
Invisible
fop-Mahboubi-2001
Oct 6, 2024
Diagnostic value of magnetic resonance imaging in fibrodysplasia ossificans progressiva.
216383287
Post
研究
ICC
Invisible
Diagnostic-value-of-magnetic-resonance
Oct 6, 2024
Evolution of heterotopic bone in fibrodysplasia ossificans progressiva: An [(18)F]NaF PET/CT study.
75139126
Post
研究
ICC
Invisible
Evolution-of-heterotopic-bone
Oct 6, 2024
Imaging assessment in fibrodysplasia ossificans progressiva: Qualitative, quantitative and questionable.
4205900
Post
研究
ICC
Invisible
Imaging-assessment-in-fop
Oct 6, 2024
Developmental anomalies of the cervical spine in patients with fibrodysplasia ossificans progressiva are distinctly different from those in patients with Klippel-Feil syndrome.
26120266
Post
研究
ICC
Invisible
Developmental-anomalies-of-the-cervical-spine
Oct 6, 2024
Analog method for radiographic assessment of heterotopic bone in fibrodysplasia ossificans progressiva.
205234147
Post
研究
ICC
Invisible
analog-method-for-radiographic
Oct 6, 2024
Classical and atypical FOP phenotypes are caused by mutations in the BMP type I receptor ACVR1.
5312799
Post
研究
ICC
Invisible
Classical-and-atypical-FOP-phenotypes
Oct 6, 2024
Acute unilateral hip pain in fibrodysplasia ossificans progressiva.
4199172
Post
研究
ICC
Invisible
Acute-unilateral-hip-pain
Oct 6, 2024
Fibrodysplasia ossificans progressiva: a disorder of osteochondrogenesis.
220889037
Post
研究
ICC
Invisible
a-disorder-of-osteochondrogenesis
Oct 6, 2024
Fibrodysplasia ossificans progressiva (FOP): A segmental progeroid syndrome.
210117364
Post
研究
ICC
Invisible
A-segmental-progeroid-syndrome
Oct 6, 2024
Joint-specific risk of impaired function in fibrodysplasia ossificans progressiva (FOP).
206285871
Post
研究
ICC
Invisible
Joint-specific-risk-of-impaired-function
Oct 6, 2024
Dysregulated BMP signaling through ACVR1 impairs digit joint development in fibrodysplasia ossificans progressiva (FOP).
227100557
Post
研究
ICC
Invisible
dysregulated-BMP-signaling-through-ACVR1
Oct 6, 2024
Lumbar puncture and surgical intervention in a child with undiagnosed fibrodysplasia ossificans progressiva.
7977125
Post
研究
ICC
Invisible
lumbar-puncture-and-surgical-intervention
Oct 6, 2024
Spatial patterns of heterotopic ossification in fibrodysplasia ossificans progressiva correlate with anatomic temperature gradients.
233457903
Post
研究
ICC
Invisible
Spatial-patterns-of-heterotopic-ossification
Oct 6, 2024
The developmental phenotype of the great toe in fibrodysplasia ossificans progressiva.
227496905
Post
研究
ICC
Invisible
the-developmental-phenotype-of-the-great-toe
Oct 6, 2024
Age and joint-specific risk of initial heterotopic ossification in patients who have fibrodysplasia ossificans progressiva.
30963376
Post
研究
ICC
Invisible
age-and joint-specific-risk
Oct 6, 2024
Skeletal malformations and developmental arthropathy in individuals who have fibrodysplasia ossificans progressiva.
204918443
Post
研究
ICC
Invisible
skeletal-malformations-and-developmental
Oct 6, 2024
Self-reported baseline phenotypes from the international fibrodysplasia ossificans progressiva (FOP) association global registry.
211135392
Post
研究
ICC
Invisible
Self-reported-baseline-phenotypes-from-ifopa
Oct 6, 2024
Natural history of fibrodysplasia ossificans progressiva: cross-sectional analysis of annotated baseline phenotypes.
145023793
Post
研究
ICC
Invisible
annotated-analysis-natural-history
Oct 6, 2024
Longitudinal patient-reported mobility assessment in fibrodysplasia ossificans progressiva (FOP).
4194733
Post
研究
ICC
Invisible
fop-longitudinal-patient-reported-mobility-assessment
Oct 6, 2024
Iatrogenic harm caused by diagnostic errors in fibrodysplasia ossificans progressiva.
389825
Post
研究
ICC
Invisible
fop-Iatrogenic-harm-caused
Oct 6, 2024
Compartment syndrome of the thigh in a patient with fibrodysplasia ossificans progressiva.
233866275
Post
研究
ICC
Invisible
compartment-syndrome-of-the-thigh
Oct 6, 2024
The natural history of heterotopic ossification in patients who have fibrodysplasia ossificans progressiva.
43604055
Post
案例
ICC
Invisible
the-natural-history-of-heterotopic-ossification
Oct 6, 2024
Genetic disorders of heterotopic ossification: fibrodysplasia ossificans progressiva and progressive osseous heteroplasia
91863394
Post
研究
ICC
Invisible
fop_and_poh
Oct 6, 2024
Fibrodysplasia ossificans progressiva
11883047
Post
研究
ICC
Invisible
fop_2008_kaplan
Oct 6, 2024
创立于2018年，最早由FOP患者明明，方方，大孔等小伙伴创立，最初希望通过QQ群汇聚分散在全国各地的FOP患者，经过大家的的努力，如今，国内已经找到100多位患者和家庭。
Post
珊瑚
Published
FOP_angel_coral
Dec 17, 2023